NQO1, NAD(P)H quinone dehydrogenase 1, 1728

N. diseases: 368; N. variants: 8
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		Immune System Diseases; Nervous System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		Nervous System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		Nervous System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.010 1.000 1 2018 2018
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0345967
Disease: Malignant mesothelioma
Malignant mesothelioma 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2018 2018
dbSNP: rs1131341
rs1131341 		0.925 0.160 16 69714966 missense variant G/A;C snv 3.2E-02 2.6E-02
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs1131341
rs1131341 		0.925 0.160 16 69714966 missense variant G/A;C snv 3.2E-02 2.6E-02
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C1827820
Disease: Fast acetylator due to N-acetyltransferase enzyme variant
Fast acetylator due to N-acetyltransferase enzyme variant 		0.010 1.000 1 2016 2016
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C1827820
Disease: Fast acetylator due to N-acetyltransferase enzyme variant
Fast acetylator due to N-acetyltransferase enzyme variant 		0.010 1.000 1 2016 2016
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C4082937
Disease: Necrotizing enterocolitis in fetus OR newborn
Necrotizing enterocolitis in fetus OR newborn 		Digestive System Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.020 1.000 2 2015 2017
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0751571
Disease: Cancer of Urinary Tract
Cancer of Urinary Tract 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2015 2015
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C3274515
Disease: Severe Bronchopulmonary Dysplasia
Severe Bronchopulmonary Dysplasia 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases 0.010 1.000 1 2015 2015
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0751571
Disease: Cancer of Urinary Tract
Cancer of Urinary Tract 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2015 2015
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0006287
Disease: Bronchopulmonary Dysplasia
Bronchopulmonary Dysplasia 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases 0.010 1.000 1 2015 2015
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		Digestive System Diseases; Neoplasms 0.030 1.000 3 2014 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		Digestive System Diseases; Neoplasms 0.030 1.000 3 2014 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma 		Digestive System Diseases; Neoplasms 0.030 1.000 3 2014 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		Immune System Diseases; Nervous System Diseases 0.020 0.500 2 2014 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		Digestive System Diseases; Neoplasms 0.020 1.000 2 2014 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		Cardiovascular Diseases 0.020 1.000 2 2014 2020
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		Digestive System Diseases; Neoplasms 0.020 1.000 2 2014 2019